HitPredict

Interactor 1: ACTA (P62736)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) (Cell growth-inhibiting gene 46 protein) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: ACTA2

Interactor 2: FBX40 (Q9UH90)
F-box only protein 40 (Muscle disease-related protein)
Gene: FBXO40

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 377 Hs			1 709
+	Hs
		1122530 ACTBL_HUMAN (4-377): 0: 712: 87.97		FBX40_HUMAN (1-709): 0: 1232: 100.00
+	Hs
		892090 ACTB_HUMAN (4-377): 0: 598: 94.12		FBX40_HUMAN (1-709): 0: 1232: 100.00
+	Hs
		932431 ACTC_HUMAN (1-377): 0: 598: 98.41		FBX40_HUMAN (1-709): 0: 1232: 100.00
+	Hs
		891911 ACTB_HUMAN (4-377): 0: 598: 94.12		FBX30_HUMAN (11-693): 0: 958: 34.31
+	Hs
		929933 ACTG_HUMAN (4-377): 0: 598: 94.39		FBX30_HUMAN (11-693): 0: 958: 34.31
+	Hs
		932271 ACTC_HUMAN (1-377): 0: 598: 98.41		FBX30_HUMAN (11-693): 0: 958: 34.31
+	Hs
		915450 ACTA_HUMAN (1-377): 0: 596: 100.00		FBX30_HUMAN (11-693): 0: 958: 34.31