HitPredict

Interactor 1: ACTA (P62737)
Actin, aortic smooth muscle (EC 3.6.4.-) (Alpha-actin-2) [Cleaved into: Actin, aortic smooth muscle, intermediate form]
Gene: Acta2

Interactor 2: LASP1 (Q61792)
LIM and SH3 domain protein 1 (LASP-1) (Metastatic lymph node gene 50 protein) (MLN 50)
Gene: LASP1

Species: Mus musculus

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.33	0.60	0.445

Property	Details
Experiments	15465019
Identification Methods	biochemical
Interaction Type	association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 377 Mm			1 263
+	Hs
		891770 ACTB_HUMAN (4-377): 0: 598: 94.12		LASP1_HUMAN (1-263): 8.1e-57: 184: 95.44
+	Dm
		361184 ACT4_DROME (1-377): 0: 647: 92.04		LASP1_DROME (41-261): 4.36e-19: 88.4: 23.32
+	Hs
		892099 ACTB_HUMAN (4-377): 0: 598: 94.12		DBNL_HUMAN (75-263): 6.35e-34: 128: 24.23
+	Hs
		932439 ACTC_HUMAN (1-377): 0: 598: 98.41		DBNL_HUMAN (75-263): 6.35e-34: 128: 24.23
+	Hs
		207785 ACTB_HUMAN (4-377): 0: 598: 94.12		PPIP1_HUMAN (3-263): 3.03e-28: 113: 16.07
+	Ce
		70025 ACT4_CAEEL (1-377): 0: 599: 93.90		SH3GH_CAEEL (36-263): 2.61e-27: 110: 16.97
+	Hs
		596202 ACTB_HUMAN (4-377): 0: 598: 94.12		NEBU_HUMAN (15-263): 7.06e-24: 102: 27.30
+	Hs
		933013 ACTS_HUMAN (1-377): 0: 598: 97.88		NRAP_HUMAN (3-220): 7.94e-24: 102: 27.48
+	Hs
		282322 ACTB_HUMAN (4-377): 0: 598: 94.12		NEBL_HUMAN (94-263): 2.51e-23: 101: 37.43
+	Hs
		930053 ACTG_HUMAN (4-377): 0: 598: 94.39		PACN2_HUMAN (44-263): 1.5e-23: 100: 19.01
+	Hs
		929985 ACTG_HUMAN (4-377): 0: 598: 94.39		SH3G2_HUMAN (59-263): 1.69e-23: 99.6: 18.35
+	Hs
		891762 ACTB_HUMAN (4-377): 0: 598: 94.12		SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46
+	Hs
		929863 ACTG_HUMAN (4-377): 0: 598: 94.39		SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46
+	Hs
		932154 ACTC_HUMAN (1-377): 0: 598: 98.41		SRC8_HUMAN (42-262): 8.52e-23: 99.2: 21.46
+	Hs
		892005 ACTB_HUMAN (4-377): 0: 598: 94.12		SRBS1_HUMAN (145-263): 5.6e-19: 88: 21.85
+	Hs
		932362 ACTC_HUMAN (1-377): 0: 598: 98.41		SRBS1_HUMAN (145-263): 5.6e-19: 88: 21.85
+	Dm
		501505 ACT1_DROME (1-377): 0: 597: 93.90		LASP1_DROME (41-261): 4.36e-19: 88.4: 23.32
+	Dm
		501447 ACT5_DROME (1-377): 0: 596: 92.57		LASP1_DROME (41-261): 4.36e-19: 88.4: 23.32
+	Dm
		361146 ACT2_DROME (1-377): 0: 595: 93.63		LASP1_DROME (41-261): 4.36e-19: 88.4: 23.32
+	Hs
		235496 ACTS_HUMAN (1-377): 0: 598: 97.88		VINEX_HUMAN (197-262): 3.25e-10: 61.9: 25.71