HitPredict

Interactor 1: AP2S1 (P62744)
AP-2 complex subunit sigma (Adaptor protein complex AP-2 subunit sigma) (Adaptor-related protein complex 2 subunit sigma) (Clathrin assembly protein 2 sigma small chain) (Clathrin coat assembly protein AP17) (Clathrin coat-associated protein AP17) (Plasma membrane adaptor AP-2 17 kDa protein) (Sigma-adaptin 3b) (Sigma2-adaptin)
Gene: AP2S1

Interactor 2: ITM2B (Q5XIE8)
Integral membrane protein 2B (Immature BRI2) (imBRI2) (Transmembrane protein BRI) (Bri) [Cleaved into: BRI2, membrane form (Mature BRI2) (mBRI2); BRI2 intracellular domain (BRI2 ICD); BRI2C, soluble form; Bri23 peptide (Bri2-23) (ABri23) (C-terminal peptide) (P23 peptide)]
Gene: ITM2B

Species: Rattus norvegicus

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	29476059
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	3

Homologous interactions

Color coding for hit scores

	1 142 Rn			1 266
+	Rn
		1104202 AP1M1_RAT (2-137): 3.99e-44: 151: 14.71		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Rn
		950917 AP2M1_RAT (1-138): 1.82e-41: 144: 15.22		ITM2B_RAT (1-266): 5.22e-154: 431: 100.00
+	Hs
		1287543 AP2M1_HUMAN (1-138): 1.82e-41: 144: 15.22		ITM2B_HUMAN (1-266): 1.32e-148: 417: 96.24