HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: MAP1A (P78559)
Microtubule-associated protein 1A (MAP-1A) (Proliferation-related protein p80) [Cleaved into: MAP1A heavy chain; MAP1 light chain LC2]
Gene: MAP1A

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.628

Property	Details
Experiments	18056259, 19637314
Identification Methods	two hybrid, pull down, affinity chromatography technology
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 2803
+	Mm
		916115 RHOB_MOUSE (1-196): 7.52e-78: 232: 100.00		MAP1A_MOUSE (1-2803): 0: 905: 77.16
+	Hs
		915702 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ITSN1_HUMAN (1332-1930): 3.27e-43: 177: 13.88
+	Hs
		894047 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ITSN1_HUMAN (1332-1930): 3.27e-43: 177: 13.88
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (339-1327): 2.95e-35: 151: 12.25
+	Hs
		900553 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		TGO1_HUMAN (342-2093): 3.41e-35: 150: 10.19
+	Ce
		104464 G5EBV3_CAEEL (2-196): 7.03e-76: 227: 48.72		UNC89_CAEEL (339-1327): 2.95e-35: 151: 12.25
+	Ce
		136800 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		UNC89_CAEEL (339-1327): 2.95e-35: 151: 12.25
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (881-1794): 1.31e-12: 76.5: 13.05
+	Hs
		925322 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		GRDN_HUMAN (1320-1644): 2.84e-12: 75.3: 20.47
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (881-1794): 1.31e-12: 76.5: 13.05
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (881-1794): 1.31e-12: 76.5: 13.05
+	Hs
		900534 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		GRDN_HUMAN (1320-1644): 2.84e-12: 75.3: 20.47
+	Hs
		915716 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		GRDN_HUMAN (1320-1644): 2.84e-12: 75.3: 20.47
+	Rn
		92842 RHOA_RAT (1-196): 3.27e-78: 233: 83.16		CTRO_RAT (1336-1644): 5.85e-12: 74.1: 20.31
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (881-1794): 1.31e-12: 76.5: 13.05
+	Hs
		545414 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		GRDN_HUMAN (1320-1644): 2.84e-12: 75.3: 20.47
+	Hs
		297809 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		K0754_HUMAN (881-1794): 1.31e-12: 76.5: 13.05
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (881-1794): 1.31e-12: 76.5: 13.05
+	Hs
		436338 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		GRDN_HUMAN (1320-1644): 2.84e-12: 75.3: 20.47
+	Hs
		951040 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		GRDN_HUMAN (1320-1644): 2.84e-12: 75.3: 20.47