HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: TOP2B (Q02880)
DNA topoisomerase 2-beta (EC 5.6.2.2) (DNA topoisomerase II, beta isozyme)
Gene: TOP2B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0070301 - cellular response to hydrogen peroxide
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1626
+	Hs
		900396 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		TOP2B_HUMAN (1-1626): 0: 1792: 100.00
+	Hs
		893918 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TOP2B_HUMAN (1-1626): 0: 1792: 100.00
+	Hs
		508929 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TOP2A_HUMAN (33-1617): 0: 1625: 66.50
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (921-1605): 7.6e-23: 109: 10.57
+	Ce
		104464 G5EBV3_CAEEL (2-196): 7.03e-76: 227: 48.72		UNC89_CAEEL (921-1605): 7.6e-23: 109: 10.57
+	Ce
		136800 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		UNC89_CAEEL (921-1605): 7.6e-23: 109: 10.57