HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: AKP13 (Q12802)
A-kinase anchor protein 13 (AKAP-13) (AKAP-Lbc) (Breast cancer nuclear receptor-binding auxiliary protein) (Guanine nucleotide exchange factor Lbc) (Human thyroid-anchoring protein 31) (Lymphoid blast crisis oncogene) (LBC oncogene) (Non-oncogenic Rho GTPase-specific GTP exchange factor) (Protein kinase A-anchoring protein 13) (PRKA13) (p47)
Gene: AKAP13

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH_16~Ras, Ras~RhoGEF
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 2813
+	Hs
		167081 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ARHGB_HUMAN (1836-2505): 4.28e-98: 353: 19.67
+	Hs
		167079 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ARHGB_HUMAN (1836-2505): 4.28e-98: 353: 19.67
+	Gg
		1141019 Q6LC82_CHICK (1-196): 2.37e-79: 236: 55.10		ARHG6_CHICK (1801-2553): 2.82e-92: 320: 12.81
+	Hs
		925416 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ARHGJ_HUMAN (1727-2443): 1.34e-89: 313: 15.40
+	Hs
		548678 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		VAV_HUMAN (1895-2582): 1.48e-77: 279: 12.70
+	Hs
		925455 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PREX1_HUMAN (1947-2653): 1.57e-73: 276: 13.52
+	Hs
		855782 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		VAV2_HUMAN (1892-2606): 5.52e-75: 272: 12.36
+	Hs
		925497 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ARHG2_HUMAN (1753-2761): 2e-73: 269: 34.62
+	Hs
		925382 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PREX2_HUMAN (1983-2652): 3.75e-68: 258: 14.12
+	Sp
		1000081 RHO1_SCHPO (1-194): 2.96e-81: 241: 68.21		RGF2_SCHPO (1527-2339): 6.3e-67: 252: 13.50
+	Hs
		925289 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ARHG6_HUMAN (1780-2553): 2.66e-70: 256: 12.86
+	Hs
		925527 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SPT13_HUMAN (1945-2387): 5.65e-69: 249: 13.94
+	Mm
		1146468 RHOA_MOUSE (1-196): 3.27e-78: 233: 83.16		PKHG5_MOUSE (1974-2347): 2.13e-66: 249: 19.20
+	Hs
		925718 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		VAV3_HUMAN (1810-2622): 3.76e-62: 233: 12.95
+	Hs
		925320 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHG6_HUMAN (1974-2492): 1.07e-50: 196: 18.38
+	Sc
		419716 RHO1_YEAST (3-186): 1.7e-88: 260: 67.39		ROM2_YEAST (1853-2283): 2.17e-36: 154: 17.37
+	Sp
		1336810 RHO5_SCHPO (4-181): 3.1e-87: 256: 67.98		RGF1_SCHPO (1970-2328): 1.93e-36: 154: 14.32
+	Sp
		1000083 RHO1_SCHPO (1-194): 2.96e-81: 241: 68.21		RGF3_SCHPO (1976-2514): 5.44e-37: 156: 17.57
+	Sp
		1000084 RHO1_SCHPO (1-194): 2.96e-81: 241: 68.21		RGF1_SCHPO (1970-2328): 1.93e-36: 154: 14.32
+	Hs
		724757 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYH9_HUMAN (1492-2562): 6.9e-29: 129: 8.90