HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: LIPA1 (Q13136)
Liprin-alpha-1 (LAR-interacting protein 1) (LIP-1) (Protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-1) (PTPRF-interacting protein alpha-1)
Gene: PPFIA1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion GO:0007165 - signal transduction GO:0098685 - Schaffer collateral - CA1 synapse
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1202
+	Hs
		925243 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		900430 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		545349 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		436281 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		950961 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		893955 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		LIPA1_HUMAN (1-1202): 8.2e-166: 526: 100.00
+	Hs
		925488 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		900754 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		915875 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		545537 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		MY18A_HUMAN (1-565): 4.66e-28: 125: 13.27
+	Hs
		724757 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		724776 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		MYH9_HUMAN (177-857): 4.68e-24: 112: 15.37
+	Hs
		925406 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		900650 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		915798 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		725138 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		545475 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		725125 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		MYH10_HUMAN (320-813): 7.13e-10: 66: 11.29
+	Hs
		436385 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62
+	Hs
		951125 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		LIPB1_HUMAN (407-643): 5.73e-09: 62.8: 11.62