HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: MYO9B (Q13459)
Unconventional myosin-IXb (Unconventional myosin-9b)
Gene: MYO9B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RA~Ras, Ras~RhoGAP
Common GO terms	GO:0005829 - cytosol GO:0007266 - Rho protein signal transduction
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 2157
+	Hs
		900443 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		436289 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		893974 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		MYO9B_HUMAN (1-2157): 0: 1563: 100.00
+	Hs
		925728 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYO5B_HUMAN (67-1775): 0: 948: 19.62
+	Hs
		564757 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		MYO5A_HUMAN (64-1775): 0: 974: 19.82
+	Hs
		120732 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		MYO5A_HUMAN (64-1775): 0: 974: 19.82
+	Ce
		93901 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		F0IWT2_CAEEL (1091-2040): 2.52e-99: 359: 20.33
+	Hs
		70663 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		70668 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		70662 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		MYO9A_HUMAN (591-2140): 2.11e-83: 308: 20.67
+	Hs
		892610 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		MYO10_HUMAN (792-1023): 2.21e-34: 147: 35.44
+	Hs
		724757 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02
+	Hs
		724776 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		MYH9_HUMAN (944-1394): 2.65e-10: 68.3: 11.02