HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PICAL (Q13492)
Phosphatidylinositol-binding clathrin assembly protein (Clathrin assembly lymphoid myeloid leukemia protein)
Gene: PICALM

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005769 - early endosome GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 652
+	Hs
		925257 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		545359 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		950976 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		892355 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		893978 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		564516 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		120422 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		PICAL_HUMAN (1-652): 0: 606: 100.00
+	Hs
		124392 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		HIP1_HUMAN (10-299): 3.19e-82: 281: 14.61
+	Hs
		124390 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		HIP1_HUMAN (10-299): 3.19e-82: 281: 14.61
+	Hs
		255309 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		HIP1R_HUMAN (13-329): 2.6e-78: 271: 12.35
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		297809 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		297819 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28
+	Hs
		120250 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		K0754_HUMAN (269-648): 1.83e-22: 105: 10.28