HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: BACD2 (Q13829)
BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 2 (hBACURD2) (BTB/POZ domain-containing protein TNFAIP1) (Protein B12) (Tumor necrosis factor, alpha-induced protein 1, endothelial)
Gene: TNFAIP1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.631

Property	Details
Experiments	33159672, 19637314
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0006915 - apoptotic process
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 316
+	Hs
		900457 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		BACD2_HUMAN (1-316): 1.75e-146: 416: 100.00
+	Hs
		915969 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		BACD3_HUMAN (1-311): 7.45e-121: 351: 70.70
+	Hs
		900745 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		BACD1_HUMAN (13-316): 1.46e-119: 348: 65.13
+	Hs
		558712 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		KCNA2_HUMAN (2-229): 1.79e-45: 162: 14.53
+	Hs
		925437 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		KCD17_HUMAN (28-180): 4.05e-42: 149: 26.42
+	Hs
		564638 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		KCNB2_HUMAN (14-202): 4.1e-44: 162: 17.41
+	Hs
		894625 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		KCTD3_HUMAN (1-130): 3.52e-26: 110: 31.34