HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: SNTB1 (Q13884)
Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43)
Gene: SNTB1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras, PH~Ras
Common GO terms	GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 538
+	Hs
		925250 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		900440 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		915650 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		545355 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		950970 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		SNTB2_HUMAN (19-537): 3.69e-141: 420: 54.41
+	Hs
		159189 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		159188 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		159149 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Hs
		159192 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		CSKP_HUMAN (28-512): 1.27e-73: 253: 10.90
+	Mm
		925797 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DLG4_MOUSE (62-203): 1.24e-23: 107: 27.89
+	Hs
		925239 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		900424 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		915639 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		545346 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		950954 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		DLG1_HUMAN (77-203): 1.17e-21: 101: 33.33
+	Hs
		900762 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG3_HUMAN (39-380): 6.2e-19: 92.7: 14.80
+	Hs
		915880 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG3_HUMAN (39-380): 6.2e-19: 92.7: 14.80
+	Hs
		925536 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MAGI1_HUMAN (26-271): 1.78e-16: 85.3: 16.00
+	Hs
		900820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MAGI1_HUMAN (26-271): 1.78e-16: 85.3: 16.00
+	Hs
		915906 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MAGI1_HUMAN (26-271): 1.78e-16: 85.3: 16.00