HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: DAG1 (Q14118)
Dystroglycan 1 (Dystroglycan) (Dystrophin-associated glycoprotein 1) [Cleaved into: Alpha-dystroglycan (Alpha-DG); Beta-dystroglycan (Beta-DG)]
Gene: DAG1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0005925 - focal adhesion GO:0030336 - negative regulation of cell migration GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 895
+	Hs
		925269 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		900460 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		545366 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		436294 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		950986 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		892363 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		893993 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		564522 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Hs
		120430 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		DAG1_HUMAN (1-895): 7.39e-154: 476: 100.00
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (37-754): 1.29e-26: 120: 10.91
+	Ce
		104464 G5EBV3_CAEEL (2-196): 7.03e-76: 227: 48.72		UNC89_CAEEL (37-754): 1.29e-26: 120: 10.91
+	Ce
		136800 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		UNC89_CAEEL (37-754): 1.29e-26: 120: 10.91
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		297809 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		297819 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10
+	Hs
		120250 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		K0754_HUMAN (548-894): 8.16e-11: 68.4: 15.10