HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: SCRIB (Q14160)
Protein scribble homolog (Scribble) (hScrib) (Protein LAP4)
Gene: SCRIB

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005886 - plasma membrane GO:0043065 - positive regulation of apoptotic process GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1630
+	Hs
		925273 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		900463 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		545370 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		950989 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		SCRIB_HUMAN (1-1630): 0: 978: 100.00
+	Hs
		915930 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		LRRC1_HUMAN (1-277): 7.16e-72: 252: 31.77
+	Dm
		776889 RAC1_DROME (1-196): 1.58e-77: 231: 53.06		SCRIB_DROME (1-258): 6.81e-66: 249: 37.98
+	Mm
		925797 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DLG4_MOUSE (812-1187): 6.74e-49: 189: 22.42
+	Hs
		900762 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		915880 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		951207 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		DLG3_HUMAN (724-947): 1.74e-19: 97.4: 31.23
+	Hs
		925239 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		900424 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		915639 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		545346 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		950954 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		DLG1_HUMAN (687-910): 4.67e-15: 82.9: 24.68
+	Hs
		925539 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		900824 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		915909 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		545571 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06
+	Hs
		951251 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		ERBIN_HUMAN (816-952): 8.76e-12: 72.8: 28.06