HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: L2GL1 (Q15334)
Lethal(2) giant larvae protein homolog 1 (LLGL) (DLG4) (Hugl-1) (Human homolog to the D-lgl gene protein)
Gene: LLGL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005886 - plasma membrane GO:0019901 - protein kinase binding
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1064
+	Hs
		925296 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		900495 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		545393 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		436316 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		951010 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		892387 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		894033 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		564540 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		120451 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		L2GL1_HUMAN (1-1064): 0: 1391: 100.00
+	Hs
		925363 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		L2GL2_HUMAN (5-979): 0: 1216: 56.97
+	Hs
		925342 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		STXB5_HUMAN (14-1064): 0: 1055: 25.47
+	Hs
		900563 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		STXB5_HUMAN (14-1064): 0: 1055: 25.47
+	Hs
		951061 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		STXB5_HUMAN (14-1064): 0: 1055: 25.47