HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PTN14 (Q15678)
Tyrosine-protein phosphatase non-receptor type 14 (EC 3.1.3.48) (Protein-tyrosine phosphatase pez)
Gene: PTPN14

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	FERM_M~Ras
Common GO terms	GO:0005634 - nucleus
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1187
+	Hs
		925302 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTN14_HUMAN (1-1187): 0: 985: 100.00
+	Hs
		925613 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41L1_HUMAN (5-713): 7.06e-142: 453: 17.33
+	Hs
		925748 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41L3_HUMAN (13-857): 2.64e-133: 435: 16.82
+	Hs
		925608 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41LB_HUMAN (18-783): 8.27e-131: 424: 17.44
+	Hs
		925247 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTPRS_HUMAN (555-1181): 7.32e-124: 423: 20.81
+	Hs
		915648 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTPRS_HUMAN (555-1181): 7.32e-124: 423: 20.81
+	Hs
		489942 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTPRF_HUMAN (364-1179): 1.6e-116: 401: 15.88
+	Hs
		489940 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTPRF_HUMAN (364-1179): 1.6e-116: 401: 15.88
+	Hs
		925235 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTPRJ_HUMAN (868-1185): 1.34e-115: 392: 29.25
+	Hs
		719697 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RADI_HUMAN (18-364): 3.83e-121: 388: 20.68
+	Hs
		915635 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTPRJ_HUMAN (868-1185): 1.34e-115: 392: 29.25
+	Hs
		547002 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		EZRI_HUMAN (18-364): 4.84e-121: 387: 20.96
+	Hs
		925637 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		E41L5_HUMAN (17-319): 2.76e-117: 382: 27.33
+	Hs
		573655 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTN1_HUMAN (891-1179): 1.76e-118: 375: 31.85
+	Hs
		925236 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		915636 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTN13_HUMAN (1-802): 3.94e-78: 286: 16.36
+	Hs
		660845 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTPRM_HUMAN (552-1183): 8.48e-71: 262: 14.80
+	Hs
		660844 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTPRM_HUMAN (552-1183): 8.48e-71: 262: 14.80
+	Hs
		617100 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTPRG_HUMAN (289-1185): 4.53e-60: 228: 12.65
+	Hs
		617097 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTPRG_HUMAN (289-1185): 4.53e-60: 228: 12.65