HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: DGKD (Q16760)
Diacylglycerol kinase delta (DAG kinase delta) (EC 2.7.1.107) (130 kDa diacylglycerol kinase) (Diglyceride kinase delta) (DGK-delta)
Gene: DGKD

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	C1_1~Ras, PH~Ras
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 1214
+	Hs
		900519 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DGKD_HUMAN (33-1214): 0: 1305: 100.00
+	Hs
		900654 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DGKH_HUMAN (20-1213): 0: 1232: 65.09
+	Hs
		915801 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DGKH_HUMAN (20-1213): 0: 1232: 65.09
+	Rn
		448411 RAC1_RAT (1-196): 2.37e-79: 236: 55.10		KPCD_RAT (11-392): 2.11e-96: 324: 19.90
+	Hs
		900406 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		KPCD_HUMAN (11-387): 4.98e-94: 318: 19.38
+	Hs
		915625 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		KPCD_HUMAN (11-387): 4.98e-94: 318: 19.38
+	Hs
		436269 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		KPCD_HUMAN (11-387): 4.98e-94: 318: 19.38
+	Ce
		1089186 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		Q17860_CAEEL (160-287): 1.04e-21: 104: 22.66
+	Hs
		856889 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DGKQ_HUMAN (153-287): 6.05e-19: 95.3: 20.00
+	Hs
		623871 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		KPCL_HUMAN (164-219): 3.82e-11: 69.4: 30.36