HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: ANO6 (Q4KMQ2)
Anoctamin-6 (Small-conductance calcium-activated nonselective cation channel) (SCAN channel) (Transmembrane protein 16F)
Gene: ANO6

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0043065 - positive regulation of apoptotic process GO:0070062 - extracellular exosome
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 910
+	Hs
		925324 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ANO6_HUMAN (1-910): 0: 1223: 100.00
+	Hs
		900536 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ANO6_HUMAN (1-910): 0: 1223: 100.00
+	Hs
		545416 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		ANO6_HUMAN (1-910): 0: 1223: 100.00
+	Hs
		436340 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		ANO6_HUMAN (1-910): 0: 1223: 100.00
+	Hs
		951043 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		ANO6_HUMAN (1-910): 0: 1223: 100.00
+	Hs
		894083 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ANO6_HUMAN (1-910): 0: 1223: 100.00
+	Hs
		120470 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		ANO6_HUMAN (1-910): 0: 1223: 100.00