HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PKHA7 (Q6IQ23)
Pleckstrin homology domain-containing family A member 7 (PH domain-containing family A member 7)
Gene: PLEKHA7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1121
+	Hs
		925629 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		900922 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Hs
		915984 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PKHA5_HUMAN (11-1074): 3.5e-95: 330: 29.45
+	Mm
		925805 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		RHG22_MOUSE (143-801): 9.06e-60: 220: 15.26
+	Hs
		925394 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG22_HUMAN (139-801): 2.51e-55: 207: 14.66
+	Hs
		900634 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RHG22_HUMAN (139-801): 2.51e-55: 207: 14.66
+	Rn
		88544 RHOA_RAT (1-196): 3.27e-78: 233: 83.16		D3ZCF5_RAT (4-213): 3.75e-53: 201: 20.26
+	Mm
		56825 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		SMUF2_MOUSE (3-213): 6.72e-48: 185: 18.18
+	Hs
		915987 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SMUF1_HUMAN (4-213): 3.11e-48: 187: 18.58
+	Hs
		876347 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		AFAD_HUMAN (329-1063): 1.33e-45: 182: 11.19
+	Hs
		125349 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		125308 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		125330 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		WWP2_HUMAN (8-203): 2.64e-43: 173: 24.39
+	Hs
		925616 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		900902 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PKHA4_HUMAN (113-465): 8.31e-38: 154: 28.84
+	Hs
		915900 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NED4L_HUMAN (59-486): 2.54e-26: 118: 12.47
+	Hs
		925520 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		808080 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		NEDD4_HUMAN (11-95): 1.03e-15: 84.6: 24.17
+	Hs
		900802 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49
+	Hs
		915895 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ITCH_HUMAN (40-305): 7.41e-17: 88.1: 14.49