HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: MPRIP (Q6WCQ1)
Myosin phosphatase Rho-interacting protein (M-RIP) (Rho-interacting protein 3) (RIP3) (p116Rip)
Gene: MPRIP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0005925 - focal adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1025
+	Hs
		900607 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MPRIP_HUMAN (1-1025): 9.29e-127: 412: 100.00
+	Hs
		925705 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SWP70_HUMAN (370-824): 7.27e-58: 212: 19.22
+	Hs
		925457 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		900722 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		915856 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG5_HUMAN (647-1019): 8.88e-54: 207: 21.61
+	Hs
		925603 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		915963 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TARA_HUMAN (231-985): 1.44e-51: 201: 35.57
+	Hs
		925356 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MRCKG_HUMAN (599-998): 1.13e-44: 178: 19.48
+	Hs
		915758 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PKHA7_HUMAN (336-980): 5.04e-41: 166: 13.51
+	Hs
		148653 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		925629 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		148608 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		148632 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		CTRO_HUMAN (195-1019): 1.45e-35: 149: 11.42
+	Hs
		915984 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PKHA5_HUMAN (318-1019): 7.56e-36: 149: 13.24
+	Hs
		724757 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MYH9_HUMAN (540-1015): 1.52e-17: 90.5: 9.66
+	Hs
		254468 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81
+	Hs
		254464 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81
+	Hs
		254467 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROCK2_HUMAN (446-1018): 6.09e-17: 88.7: 11.81
+	Hs
		915964 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SLK_HUMAN (178-999): 9.15e-17: 87.8: 10.02
+	Hs
		255309 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		HIP1R_HUMAN (626-929): 1.25e-09: 64.5: 19.56