HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: RTKN2 (Q8IZC4)
Rhotekin-2 (Pleckstrin homology domain-containing family K member 1) (PH domain-containing family K member 1)
Gene: RTKN2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007165 - signal transduction
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 609
+	Hs
		436397 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		RTKN2_HUMAN (1-609): 0: 889: 100.00
+	Mm
		1207978 RHOA_MOUSE (1-196): 3.27e-78: 233: 83.16		RTKN_MOUSE (18-518): 0: 612: 39.37
+	Rn
		901291 RHOA_RAT (1-196): 3.27e-78: 233: 83.16		RTKN_RAT (18-518): 0: 605: 41.54
+	Hs
		925570 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RTKN_HUMAN (19-518): 0: 602: 40.43
+	Hs
		900848 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RTKN_HUMAN (19-518): 0: 602: 40.43
+	Hs
		915929 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		RTKN_HUMAN (19-518): 0: 602: 40.43
+	Hs
		436482 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		RTKN_HUMAN (19-518): 0: 602: 40.43
+	Hs
		900944 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ANLN_HUMAN (26-399): 2.74e-102: 336: 18.95
+	Hs
		916000 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ANLN_HUMAN (26-399): 2.74e-102: 336: 18.95
+	Hs
		436528 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		ANLN_HUMAN (26-399): 2.74e-102: 336: 18.95
+	Hs
		894475 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ANLN_HUMAN (26-399): 2.74e-102: 336: 18.95
+	Dm
		816388 RHO1_DROME (1-196): 5.31e-75: 225: 80.10		ANLN_DROME (18-398): 3.79e-98: 327: 16.39
+	Ce
		104473 G5EBV3_CAEEL (2-196): 7.03e-76: 227: 48.72		ANI1_CAEEL (46-400): 1.08e-94: 316: 15.65