HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: UNC5B (Q8IZJ1)
Netrin receptor UNC5B (Protein unc-5 homolog 2) (Protein unc-5 homolog B) (p53-regulated receptor for death and life protein 1) (p53RDL1)
Gene: UNC5B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0001525 - angiogenesis GO:0005886 - plasma membrane GO:0006915 - apoptotic process
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 945
+	Hs
		925426 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		900676 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		892478 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		894201 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		564606 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		UNC5B_HUMAN (1-945): 0: 962: 100.00
+	Hs
		306910 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		UNC5C_HUMAN (32-944): 0: 864: 63.75
+	Hs
		900411 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ZO1_HUMAN (405-656): 2.76e-51: 198: 20.63
+	Hs
		915627 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ZO1_HUMAN (405-656): 2.76e-51: 198: 20.63
+	Hs
		893933 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ZO1_HUMAN (405-656): 2.76e-51: 198: 20.63
+	Hs
		925776 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		901110 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		916112 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		436602 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		894644 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		894276 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		PXDN_HUMAN (2-262): 8.33e-41: 165: 17.80
+	Hs
		564764 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		ROBO1_HUMAN (2-257): 1.06e-41: 168: 17.16
+	Hs
		915989 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO2_HUMAN (9-177): 5.33e-19: 95.1: 11.41
+	Hs
		894044 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		MYLK_HUMAN (37-133): 4.45e-11: 69.3: 13.00