HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PARD3 (Q8TEW0)
Partitioning defective 3 homolog (PAR-3) (PARD-3) (Atypical PKC isotype-specific-interacting protein) (ASIP) (CTCL tumor antigen se2-5) (PAR3-alpha)
Gene: PARD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0007155 - cell adhesion
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1356
+	Hs
		925463 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		900726 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PARD3_HUMAN (1-1356): 0: 709: 100.00
+	Hs
		900727 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Hs
		915861 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PAR3L_HUMAN (1-1354): 5.88e-101: 352: 32.37
+	Hs
		925725 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		916070 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NEB1_HUMAN (36-1074): 1.37e-60: 229: 11.36
+	Hs
		915880 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DLG3_HUMAN (556-1119): 1.21e-27: 123: 13.01
+	Mm
		925797 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DLG4_MOUSE (540-699): 7.89e-23: 107: 27.98
+	Hs
		925236 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		925536 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		900421 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		915636 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PTN13_HUMAN (39-368): 1.59e-16: 88.1: 12.50
+	Hs
		915906 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MAGI1_HUMAN (354-780): 1.36e-16: 88.1: 14.16
+	Hs
		900710 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		915848 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		INADL_HUMAN (28-397): 1.09e-15: 85.1: 11.14
+	Hs
		900411 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		915627 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ZO1_HUMAN (271-586): 1.19e-11: 72: 14.06
+	Hs
		925273 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		900463 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75
+	Hs
		915673 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SCRIB_HUMAN (66-355): 5.59e-09: 63.1: 12.75