HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: FRS2 (Q8WU20)
Fibroblast growth factor receptor substrate 2 (FGFR substrate 2) (FGFR-signaling adaptor SNT) (Suc1-associated neurotrophic factor target 1) (SNT-1)
Gene: FRS2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	16

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 508
+	Hs
		925468 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		900731 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		545522 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		436429 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		951184 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		892505 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		894251 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		564628 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		FRS2_HUMAN (1-508): 0: 590: 100.00
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297809 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		297819 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29
+	Hs
		120250 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		K0754_HUMAN (89-473): 1.17e-17: 89: 12.29