HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: DEP1B (Q8WUY9)
DEP domain-containing protein 1B (HBV X-transactivated gene 8 protein) (HBV XAg-transactivated protein 8)
Gene: DEPDC1B

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.80	0.675

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~RhoGAP
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 529
+	Hs
		925474 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DEP1B_HUMAN (1-529): 0: 559: 100.00
+	Hs
		147862 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG33_HUMAN (173-520): 5.6e-71: 248: 16.02
+	Hs
		925329 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG15_HUMAN (126-393): 3.82e-69: 231: 13.50
+	Hs
		925354 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG17_HUMAN (39-508): 4.13e-64: 226: 15.06
+	Mm
		925803 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		RHG32_MOUSE (173-497): 1.14e-61: 221: 14.54
+	Hs
		64688 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG32_HUMAN (173-497): 2.77e-61: 220: 14.54
+	Hs
		200213 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SRGP3_HUMAN (66-474): 1.81e-60: 217: 11.16
+	Hs
		925192 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG04_HUMAN (50-412): 8.1e-61: 217: 12.40
+	Mm
		925802 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		CHIO_MOUSE (169-393): 5.7e-65: 216: 12.72
+	Hs
		925395 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SRGP1_HUMAN (66-474): 6.27e-59: 213: 12.77
+	Hs
		856140 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CHIO_HUMAN (169-393): 3.1e-61: 210: 12.72
+	Hs
		551044 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		CHIN_HUMAN (169-393): 9.36e-61: 208: 14.47
+	Hs
		925378 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG27_HUMAN (25-394): 2.41e-57: 207: 13.17
+	Hs
		925420 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG12_HUMAN (78-393): 5.6e-55: 200: 16.31
+	Hs
		925314 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG44_HUMAN (133-437): 1.2e-54: 198: 13.59
+	Hs
		925688 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		GMIP_HUMAN (194-503): 7.56e-54: 197: 13.02
+	Hs
		925319 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG31_HUMAN (243-402): 4.62e-35: 142: 20.71
+	Sp
		195119 RHO1_SCHPO (1-194): 2.96e-81: 241: 68.21		RGA1_SCHPO (229-508): 8.03e-19: 92.5: 14.63
+	Hs
		925394 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG22_HUMAN (255-396): 3.52e-19: 92.9: 15.75
+	Mm
		925805 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		RHG22_MOUSE (255-420): 6.69e-19: 92.2: 16.38