HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: US6NL (Q92738)
USP6 N-terminal-like protein (Related to the N-terminus of tre) (RN-tre)
Gene: USP6NL

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	RabGAP-TBC~Ras
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	19

Homologous interactions

Color coding for hit scores

	1 196 Hs			1 828
+	Hs
		925494 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		900761 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		545541 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		951204 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		892524 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		894279 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		564635 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		120571 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		US6NL_HUMAN (1-828): 0: 882: 100.00
+	Hs
		715076 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		UBP6_HUMAN (1-554): 2.62e-120: 397: 30.45
+	Hs
		715074 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		UBP6_HUMAN (1-554): 2.62e-120: 397: 30.45
+	Hs
		915938 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TB10A_HUMAN (27-503): 9.92e-102: 326: 24.07
+	Mm
		925784 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		EVI5_MOUSE (17-591): 6.72e-97: 322: 17.30
+	Hs
		925323 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		915717 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		892404 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		232655 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBCD4_HUMAN (1-455): 1.43e-88: 307: 19.40
+	Ce
		975574 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		Q23419_CAEEL (32-350): 9.62e-85: 291: 21.86
+	Hs
		564554 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		TB10B_HUMAN (23-459): 7.98e-93: 311: 23.87
+	Hs
		894392 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		TBD2A_HUMAN (5-368): 1.26e-82: 285: 22.82