HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: ERBIN (Q96RT1)
Erbin (Densin-180-like protein) (Erbb2-interacting protein) (Protein LAP2)
Gene: ERBIN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PDZ~Ras
Common GO terms	GO:0005634 - nucleus GO:0005886 - plasma membrane GO:0007155 - cell adhesion GO:0007165 - signal transduction
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1412
+	Hs
		925539 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		900824 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		545571 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		436472 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		951251 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		892548 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		894337 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		564652 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		ERBIN_HUMAN (8-1412): 0: 907: 100.00
+	Hs
		925273 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		900463 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		915673 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		545370 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		436297 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		950989 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		892367 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		893999 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		564526 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		120433 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		SCRIB_HUMAN (357-1409): 1.57e-40: 166: 12.00
+	Hs
		915930 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		LRRC1_HUMAN (311-709): 1.39e-23: 108: 15.97
+	Dm
		776889 RAC1_DROME (1-196): 1.58e-77: 231: 53.06		SCRIB_DROME (1095-1408): 4.08e-16: 86.8: 16.82