HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: SGIP1 (Q9BQI5)
SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein)
Gene: SGIP1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 828
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (295-764): 1.24e-22: 106: 12.34
+	Ce
		104464 G5EBV3_CAEEL (2-196): 7.03e-76: 227: 48.72		UNC89_CAEEL (295-764): 1.24e-22: 106: 12.34
+	Ce
		136800 RHO1_CAEEL (1-196): 4.36e-75: 225: 78.57		UNC89_CAEEL (295-764): 1.24e-22: 106: 12.34
+	Hs
		297823 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		297820 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		297822 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		297812 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		297809 RHOC_HUMAN (1-196): 8.84e-76: 227: 83.16		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		297827 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		297819 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		925230 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		915631 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		545343 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		894572 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		MUC12_HUMAN (164-783): 2.68e-12: 73.4: 8.71
+	Hs
		950948 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		892336 RAC3_HUMAN (1-179): 1.15e-74: 224: 57.54		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		893940 CDC42_HUMAN (1-196): 1.35e-74: 224: 49.49		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		120250 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		K0754_HUMAN (449-802): 3.52e-17: 89.2: 10.87
+	Hs
		564496 RHOQ_HUMAN (2-195): 6.71e-68: 207: 51.74		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53
+	Hs
		120408 RHOD_HUMAN (7-182): 3.37e-66: 203: 53.98		FCHO2_HUMAN (66-350): 5.77e-11: 68.4: 29.53