HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: DOCK9 (Q9BZ29)
Dedicator of cytokinesis protein 9 (Cdc42 guanine nucleotide exchange factor zizimin-1) (Zizimin-1)
Gene: DOCK9

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	DHR-2_Lobe_B~Ras, DHR-2_Lobe_C~Ras, PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 2069
+	Hs
		925588 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK9_HUMAN (1-2069): 0: 2505: 100.00
+	Hs
		925332 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOC11_HUMAN (11-2068): 0: 2189: 58.38
+	Hs
		915729 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DOC11_HUMAN (11-2068): 0: 2189: 58.38
+	At
		1105136 RAC4_ARATH (1-179): 5.45e-87: 255: 49.16		SPK1_ARATH (283-2064): 0: 1196: 20.61
+	Mm
		925807 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		DOCK1_MOUSE (395-1220): 0: 621: 14.22
+	Hs
		925276 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK1_HUMAN (395-1220): 0: 616: 13.87
+	Hs
		915674 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DOCK1_HUMAN (395-1220): 0: 616: 13.87
+	Hs
		925429 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK4_HUMAN (395-1225): 3.36e-176: 591: 14.85
+	Hs
		925486 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK2_HUMAN (395-1220): 3.51e-175: 585: 13.09
+	Hs
		925620 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK5_HUMAN (395-1224): 1.09e-163: 553: 13.46
+	Hs
		925425 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK3_HUMAN (395-1225): 1.76e-145: 503: 14.53
+	Hs
		925254 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		900445 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		915656 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		GAB1_HUMAN (171-470): 2.06e-66: 242: 17.39
+	Hs
		925526 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Hs
		915899 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		DOCK7_HUMAN (11-205): 1.33e-48: 194: 24.88
+	Hs
		925518 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK6_HUMAN (9-176): 1.25e-43: 177: 23.37
+	Hs
		925448 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		DOCK8_HUMAN (7-167): 4.89e-42: 172: 21.23
+	Hs
		925632 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA1_HUMAN (149-366): 8.42e-36: 143: 18.83
+	Hs
		915986 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PKHA1_HUMAN (149-366): 8.42e-36: 143: 18.83