HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: OSBL8 (Q9BZF1)
Oxysterol-binding protein-related protein 8 (ORP-8) (OSBP-related protein 8)
Gene: OSBPL8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	34079125
Identification Methods	proximity labelling technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol GO:0030336 - negative regulation of cell migration
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 889
+	Hs
		925589 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		900866 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		545597 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		951303 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		OSBL8_HUMAN (1-889): 0: 1210: 100.00
+	Hs
		545575 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		OSBL9_HUMAN (209-743): 5.35e-159: 484: 30.32
+	Hs
		925615 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		915945 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		OSBL6_HUMAN (250-756): 1.6e-143: 450: 20.96
+	Hs
		900901 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		915974 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		545617 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		OSBL3_HUMAN (250-757): 1.65e-143: 449: 18.81
+	Hs
		925582 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		900859 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		545593 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		951289 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		OSB10_HUMAN (283-749): 1.96e-139: 435: 29.46
+	Hs
		925581 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		900858 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		915936 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		545592 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Hs
		951288 RHOG_HUMAN (1-196): 8.84e-76: 227: 51.53		OSB11_HUMAN (345-749): 6.21e-130: 409: 29.62
+	Sc
		419682 RHO1_YEAST (3-186): 1.7e-88: 260: 67.39		KES1_YEAST (399-733): 5.95e-92: 299: 26.83