HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: PKHA5 (Q9HAU0)
Pleckstrin homology domain-containing family A member 5 (PH domain-containing family A member 5) (Phosphoinositol 3-phosphate-binding protein 2) (PEPP-2)
Gene: PLEKHA5

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	34079125, 31871319
Identification Methods	proximity labelling technology, affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	PH~Ras
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 1116
+	Hs
		925629 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA5_HUMAN (1-1116): 0: 609: 100.00
+	Hs
		915758 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PKHA7_HUMAN (2-1059): 8.31e-125: 412: 27.32
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (727-1109): 1.99e-56: 217: 12.25
+	Mm
		925805 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		RHG22_MOUSE (129-757): 1.01e-46: 181: 13.50
+	Hs
		925536 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Mm
		56825 RAC1_MOUSE (1-196): 2.37e-79: 236: 55.10		SMUF2_MOUSE (12-202): 1.01e-43: 173: 14.85
+	Rn
		88544 RHOA_RAT (1-196): 3.27e-78: 233: 83.16		D3ZCF5_RAT (11-202): 1.3e-44: 175: 17.07
+	Hs
		915906 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MAGI1_HUMAN (1-1111): 1.6e-43: 175: 9.66
+	Hs
		925394 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		RHG22_HUMAN (139-751): 3.05e-43: 170: 15.09
+	Hs
		900634 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		RHG22_HUMAN (139-751): 3.05e-43: 170: 15.09
+	Hs
		925632 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		915986 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		PKHA1_HUMAN (161-359): 9.87e-42: 160: 19.43
+	Hs
		925616 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		PKHA4_HUMAN (142-851): 4.17e-38: 155: 16.85
+	Hs
		900607 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		915771 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		MPRIP_HUMAN (95-395): 8.25e-38: 155: 13.86
+	Hs
		925520 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ITCH_HUMAN (9-234): 1.29e-27: 123: 15.93
+	Hs
		125349 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51
+	Hs
		915895 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ITCH_HUMAN (9-234): 1.29e-27: 123: 15.93
+	Hs
		125308 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51
+	Hs
		125330 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		WWP2_HUMAN (10-213): 2.29e-27: 122: 19.51