HitPredict

Interactor 1: RHOB (P62745)
Rho-related GTP-binding protein RhoB (Rho cDNA clone 6) (h6)
Gene: RHOB

Interactor 2: NECT3 (Q9NQS3)
Nectin-3 (CDw113) (Nectin cell adhesion molecule 3) (Poliovirus receptor-related protein 3) (CD antigen CD113)
Gene: NECTIN3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	31871319
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ras~V-set
Common GO terms	GO:0005886 - plasma membrane
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 196 Hs			1 549
+	Hs
		925647 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		900943 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		545637 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		NECT3_HUMAN (49-549): 5.39e-105: 327: 100.00
+	Hs
		925521 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		900803 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		915896 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		925492 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		545561 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		KIRR1_HUMAN (41-509): 3.57e-62: 219: 17.59
+	Hs
		900759 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		915877 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		545540 RAC2_HUMAN (1-196): 7.63e-77: 230: 53.57		NECT2_HUMAN (25-360): 1.8e-62: 215: 28.81
+	Hs
		530163 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		NCAM1_HUMAN (2-511): 1.22e-57: 208: 12.43
+	Hs
		915725 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SDK2_HUMAN (39-476): 2.32e-34: 140: 12.92
+	Hs
		900635 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		915792 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		SDK1_HUMAN (5-499): 7.02e-34: 139: 13.50
+	Hs
		925776 RAC1_HUMAN (1-196): 2.37e-79: 236: 55.10		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		901110 RHOA_HUMAN (1-196): 7.19e-78: 232: 83.67		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		916112 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO1_HUMAN (264-548): 5.78e-25: 112: 10.39
+	Hs
		915989 RHOB_HUMAN (1-196): 7.52e-78: 232: 100.00		ROBO2_HUMAN (264-503): 6.31e-25: 111: 12.11
+	Ce
		136793 RAC1_CAEEL (1-196): 5.29e-80: 238: 53.57		UNC89_CAEEL (69-289): 2.15e-12: 72.4: 8.60