HitPredict

Interactor 1: RS6 (P62753)
Small ribosomal subunit protein eS6 (40S ribosomal protein S6) (Phosphoprotein NP33)
Gene: RPS6

Interactor 2: LARP7 (Q4G0J3)
La-related protein 7 (La ribonucleoprotein domain family member 7) (hLARP7) (P-TEFb-interaction protein for 7SK stability) (PIP7S)
Gene: LARP7

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.78	0.60	0.686

Property	Details
Experiments	26725010, 29845934, 34079125, 33961781
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005829 - cytosol GO:1990904 - ribonucleoprotein complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 249 Hs			1 582
+	Hs
		403167 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		LA_HUMAN (24-365): 5.96e-44: 163: 18.83
+	Hs
		516447 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		PABP1_HUMAN (1-405): 1.94e-40: 157: 10.29
+	Hs
		916831 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		MK67I_HUMAN (93-358): 1.25e-39: 148: 19.42
+	Hs
		916917 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		RBM28_HUMAN (40-343): 2.97e-23: 106: 13.84
+	Sc
		376593 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		PABP_YEAST (9-243): 8.44e-33: 134: 13.47
+	Hs
		916654 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		LARP1_HUMAN (29-114): 6.35e-13: 73.8: 40.23