HitPredict

Interactor 1: RS6 (P62753)
Small ribosomal subunit protein eS6 (40S ribosomal protein S6) (Phosphoprotein NP33)
Gene: RPS6

Interactor 2: DDX18 (Q9NVP1)
ATP-dependent RNA helicase DDX18 (EC 3.6.4.13) (DEAD box protein 18) (Myc-regulated DEAD box protein) (MrDb)
Gene: DDX18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	29568061, 34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0016020 - membrane
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 249 Hs			1 670
+	Hs
		916554 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX10_HUMAN (124-621): 9.53e-167: 501: 41.60
+	Sc
		479917 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		DBP4_YEAST (141-662): 8.19e-161: 483: 35.85
+	Hs
		916708 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX55_HUMAN (176-668): 5.77e-136: 413: 34.05
+	Hs
		133963 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX3X_HUMAN (17-564): 1.37e-130: 401: 22.59
+	Sc
		480288 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		HAS1_YEAST (142-641): 8.13e-140: 420: 57.69
+	Sc
		479938 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		DBP2_YEAST (75-553): 1.02e-125: 385: 24.29
+	Hs
		916872 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX31_HUMAN (87-619): 1.02e-81: 278: 33.71
+	Hs
		916767 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX27_HUMAN (121-574): 3.56e-56: 206: 34.88
+	Hs
		917003 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX49_HUMAN (195-565): 1.87e-54: 195: 33.95
+	Sc
		479958 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		SPB4_YEAST (197-618): 1.28e-57: 207: 32.29
+	Sc
		480004 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		DRS1_YEAST (191-523): 3.57e-56: 205: 38.30