HitPredict

Interactor 1: RS6 (P62753)
Small ribosomal subunit protein eS6 (40S ribosomal protein S6) (Phosphoprotein NP33)
Gene: RPS6

Interactor 2: DDX56 (Q9NY93)
Probable ATP-dependent RNA helicase DDX56 (EC 3.6.4.13) (ATP-dependent 61 kDa nucleolar RNA helicase) (DEAD box protein 21) (DEAD box protein 56)
Gene: DDX56

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	29568061, 34079125, 33961781
Identification Methods	proximity labelling technology, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005730 - nucleolus GO:0005829 - cytosol GO:0006364 - rRNA processing and 1 others more... GO:0016020 - membrane
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 249 Hs			1 547
+	Sc
		480327 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		DBP9_YEAST (4-534): 1.72e-146: 436: 41.13
+	Hs
		133963 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX3X_HUMAN (6-422): 2.4e-120: 371: 25.23
+	Sc
		479938 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		DBP2_YEAST (4-415): 2.96e-129: 389: 24.70
+	Hs
		916767 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX27_HUMAN (5-465): 7.48e-52: 191: 30.44
+	Hs
		640413 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		DDX6_HUMAN (9-407): 9.42e-46: 169: 29.78
+	Hs
		757546 RS6_HUMAN (1-249): 9.61e-112: 322: 100.00		IF4A3_HUMAN (9-403): 3.82e-44: 163: 28.12
+	Sc
		480004 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		DRS1_YEAST (9-394): 6.69e-49: 182: 30.67
+	Dm
		612566 RS6_DROME (1-238): 3.3e-103: 301: 76.57		DDX6_DROME (3-407): 2.68e-45: 167: 29.80
+	Sc
		479864 RS6A_YEAST (1-239): 1.54e-97: 286: 62.76		IF4A_YEAST (3-405): 6.51e-44: 162: 31.39