HitPredict

Interactor 1: H4 (P62799)
Histone H4
Gene: H4

Interactor 2: H32 (P84233)
Histone H3.2
Gene: H32

Species: Xenopus laevis

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.63	1.00	0.799

Property	Details
Experiments	32631887, 17293877
Identification Methods	pull down, static light scattering, molecular sieving
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	CENP-T_C~Histone
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 103 Xl			1 136
+	Hs
		917093 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H31_HUMAN (1-136): 1.98e-62: 189: 99.27
+	Mm
		918236 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H31_MOUSE (1-136): 1.98e-62: 189: 99.27
+	Hs
		917352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H31T_HUMAN (1-136): 8.3e-62: 187: 96.32
+	Xl
		917056 H4_XENLA (1-103): 1.38e-48: 151: 100.00		Q92133_XENLA (1-136): 1.59e-61: 186: 99.27
+	Hs
		917112 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H33_HUMAN (1-136): 1.59e-61: 186: 97.06
+	Hs
		917483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Mm
		918239 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H32_MOUSE (1-136): 3.73e-61: 186: 100.00
+	Mm
		918240 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		H33_MOUSE (1-136): 1.59e-61: 186: 97.06
+	Ce
		445733 H4_CAEEL (1-103): 1.41e-48: 151: 99.03		H3_CAEEL (1-136): 8.66e-61: 184: 97.06
+	Hs
		917448 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H3C_HUMAN (1-136): 8.83e-59: 179: 94.12
+	Sp
		448920 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		H31_SCHPO (1-136): 2.22e-59: 181: 91.91
+	Hs
		1174638 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		H32_HUMAN (1-136): 3.73e-61: 186: 100.00
+	Sc
		356652 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H3_YEAST (1-136): 7.77e-56: 172: 88.97
+	Ce
		711990 H4_CAEEL (1-103): 1.41e-48: 151: 99.03		HCP3L_CAEEL (11-131): 4.03e-44: 146: 45.16
+	Hs
		828186 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CENPA_HUMAN (9-133): 2.85e-44: 143: 50.00
+	Kl
		1150023 Q6CMU6_KLULA (18-103): 9.41e-42: 134: 91.86		CENPA_KLULA (14-134): 9.24e-44: 143: 54.84
+	Sc
		356401 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CENPA_YEAST (18-134): 1.58e-41: 139: 56.67