HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: RING1 (Q06587)
E3 ubiquitin-protein ligase RING1 (EC 2.3.2.27) (Polycomb complex protein RING1) (RING finger protein 1) (RING-type E3 ubiquitin transferase RING1) (Really interesting new gene 1 protein)
Gene: RING1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 406
+	Hs
		917796 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		RING2_HUMAN (8-406): 4.9e-100: 302: 54.25
+	Hs
		717645 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BMI1_HUMAN (31-378): 4.06e-63: 207: 14.16
+	Mm
		918264 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		RN138_MOUSE (31-190): 1.32e-45: 159: 18.68
+	Hs
		917809 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BARD1_HUMAN (4-335): 2.56e-39: 151: 13.35
+	Hs
		917875 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PCGF6_HUMAN (31-157): 1.02e-40: 149: 23.08
+	Hs
		917840 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PCGF1_HUMAN (25-133): 3.54e-40: 145: 25.00
+	Hs
		749335 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRCA1_HUMAN (33-361): 4.24e-35: 139: 15.63