HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: BPTF (Q12830)
Nucleosome-remodeling factor subunit BPTF (Bromodomain and PHD finger-containing transcription factor) (Fetal Alz-50 clone 1 protein) (Fetal Alzheimer antigen)
Gene: BPTF

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.654

Property	Details
Experiments	30804502, 21596426
Identification Methods	affinity chromatography technology, pull down, unspecified method, x-ray crystallography, peptide array, fluorescence polarization spectroscopy, isothermal titration calorimetry
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0070062 - extracellular exosome
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Hs			1 3046
+	Hs
		802415 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ATRX_HUMAN (379-1565): 1.21e-110: 399: 11.94
+	At
		886860 H4_ARATH (1-103): 3.47e-48: 150: 98.06		MBD9_ARATH (348-789): 2.79e-58: 226: 21.01
+	Hs
		918100 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BAZ2B_HUMAN (2300-3033): 2.68e-52: 207: 15.76
+	Hs
		917468 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ANR11_HUMAN (621-2482): 2.09e-49: 198: 9.14
+	Hs
		917170 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		EP300_HUMAN (1930-3035): 2.55e-49: 197: 11.62
+	Hs
		917792 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MINT_HUMAN (983-2856): 7.38e-47: 189: 8.46
+	Hs
		918101 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BAZ2A_HUMAN (2341-3038): 1.92e-43: 178: 15.08
+	Hs
		170320 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TIF1A_HUMAN (383-610): 8.36e-41: 168: 19.23
+	Hs
		917689 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT2B_HUMAN (2930-3030): 6.65e-41: 167: 47.53
+	Hs
		918130 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ZMYD8_HUMAN (2811-3032): 9.21e-40: 165: 24.61
+	Hs
		917688 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT2A_HUMAN (2930-3030): 6.22e-40: 164: 49.51
+	Hs
		631388 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD2_HUMAN (2746-3032): 7.09e-28: 125: 20.14
+	Hs
		917299 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD3_HUMAN (2905-3032): 5.45e-26: 119: 27.07
+	Hs
		917667 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TITIN_HUMAN (1259-2946): 5.69e-25: 117: 7.72
+	Mm
		918262 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		BRDT_MOUSE (2911-3025): 6.98e-25: 116: 30.83
+	Hs
		917182 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD3_HUMAN (356-439): 2.17e-18: 95.6: 33.33
+	Hs
		917684 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBP_HUMAN (1558-2670): 1.8e-12: 76: 8.05
+	Hs
		244235 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD4_HUMAN (2936-3028): 1.03e-10: 70.1: 41.05
+	Hs
		256395 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PHF2_HUMAN (2868-2924): 3.51e-10: 68.2: 47.37
+	Hs
		917780 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CIC_HUMAN (1024-2323): 3.62e-09: 65.2: 8.69