HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: CHD3 (Q12873)
Chromodomain-helicase-DNA-binding protein 3 (CHD-3) (EC 3.6.4.12) (ATP-dependent helicase CHD3) (Mi-2 autoantigen 240 kDa protein) (Mi2-alpha) (Zinc finger helicase) (hZFH)
Gene: CHD3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.68	1.00	0.827

Property	Details
Experiments	28977666, 27248496, 30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0003677 - DNA binding GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 2000
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (132-1922): 0: 1552: 69.84
+	Hs
		917364 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD9_HUMAN (20-1898): 0: 865: 22.10
+	Hs
		917635 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD6_HUMAN (218-1804): 0: 861: 24.77
+	Hs
		917965 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD8_HUMAN (84-1804): 0: 851: 22.96
+	Hs
		918062 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD7_HUMAN (503-1804): 0: 837: 28.86
+	Sc
		356350 H4_YEAST (18-103): 6.13e-41: 132: 90.70		CHD1_YEAST (539-1691): 0: 817: 29.78
+	Hs
		229352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA5_HUMAN (584-1612): 0: 778: 27.17
+	Dm
		950383 H4_DROME (1-103): 4.51e-48: 150: 99.03		ISWI_DROME (603-1623): 0: 771: 26.16
+	Sp
		144535 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		HRP3_SCHPO (538-1623): 0: 769: 30.09
+	Hs
		151483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD2_HUMAN (540-1666): 0: 733: 31.02
+	Sc
		356774 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW2_YEAST (726-1280): 3.89e-124: 423: 43.87