HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: TCOF (Q13428)
Treacle protein (Treacher Collins syndrome protein)
Gene: TCOF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	30804502, 34349018
Identification Methods	affinity chromatography technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005654 - nucleoplasm GO:0046982 - protein heterodimerization activity
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1488
+	Hs
		917444 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		NIPBL_HUMAN (429-1488): 4.56e-56: 217: 10.13
+	Hs
		917267 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MDC1_HUMAN (238-1377): 7.73e-52: 203: 12.82
+	Hs
		807676 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MAP1B_HUMAN (41-1111): 4.34e-44: 178: 10.34
+	Hs
		152623 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KMT2D_HUMAN (751-1487): 2.54e-13: 77.6: 8.66
+	Hs
		917270 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		NCOA6_HUMAN (59-1090): 2.41e-13: 77.6: 8.41
+	Hs
		917476 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SRCAP_HUMAN (497-1303): 7.2e-11: 69.8: 13.18
+	Hs
		917128 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ANK2_HUMAN (195-1161): 9.81e-10: 65.9: 15.17
+	Hs
		918222 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		NCOR2_HUMAN (337-1488): 2.04e-09: 65: 8.15
+	Hs
		917565 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MILK2_HUMAN (420-909): 2.21e-09: 64.4: 19.48
+	Hs
		917667 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TITIN_HUMAN (91-778): 3.15e-09: 64.2: 9.45