HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: WRN (Q14191)
Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN (DNA helicase, RecQ-like type 3) (RecQ protein-like 2) (Werner syndrome protein) [Includes: 3'-5' exonuclease (EC 3.1.-.-); ATP-dependent helicase (EC 5.6.2.4) (DNA 3'-5' helicase WRN)]
Gene: WRN

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1432
+	Hs
		295517 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		RECQ5_HUMAN (525-1181): 4.27e-145: 470: 24.96
+	Hs
		917536 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX42_HUMAN (309-900): 1.25e-131: 432: 13.75
+	Hs
		867560 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BLM_HUMAN (221-1158): 8.03e-120: 410: 21.16
+	Hs
		294652 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		RECQ4_HUMAN (530-878): 2.42e-118: 402: 29.95
+	Hs
		917490 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX46_HUMAN (278-1201): 6e-120: 402: 12.60
+	Hs
		133964 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX3X_HUMAN (354-901): 6.63e-119: 389: 14.85
+	Hs
		917690 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX17_HUMAN (469-955): 1.98e-117: 387: 16.54
+	Hs
		571390 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DDX5_HUMAN (469-892): 8.41e-112: 368: 16.96