HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: MCM6 (Q14566)
DNA replication licensing factor MCM6 (EC 3.6.4.12) (p105MCM)
Gene: MCM6

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.80	0.60	0.694

Property	Details
Experiments	28514442, 27248496, 33961781, 19862764
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 821
+	Sc
		356602 H4_YEAST (18-103): 6.13e-41: 132: 90.70		MCM6_YEAST (2-821): 0: 717: 40.07
+	Hs
		708595 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MCM5_HUMAN (2-741): 0: 653: 27.42
+	Hs
		627231 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MCM3_HUMAN (18-813): 0: 639: 25.76
+	Hs
		708859 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MCM7_HUMAN (22-713): 0: 634: 28.88
+	Sc
		356303 H4_YEAST (18-103): 6.13e-41: 132: 90.70		MCM5_YEAST (18-663): 0: 652: 28.81
+	Hs
		708413 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MCM4_HUMAN (2-736): 0: 632: 27.70
+	Hs
		832321 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MCM2_HUMAN (22-732): 0: 628: 28.40
+	Sc
		356306 H4_YEAST (18-103): 6.13e-41: 132: 90.70		MCM4_YEAST (13-753): 0: 601: 27.88