HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: MAD4 (Q14582)
Max dimerization protein 4 (Max dimerizer 4) (Class C basic helix-loop-helix protein 12) (bHLHc12) (Max-associated protein 4) (Max-interacting transcriptional repressor MAD4)
Gene: MXD4

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 209
+	Hs
		840203 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MXI1_HUMAN (1-196): 3.76e-55: 176: 50.23
+	Hs
		917801 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MNT_HUMAN (26-199): 2.22e-43: 154: 24.57
+	Mm
		348414 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		MYC_MOUSE (36-135): 1.68e-31: 120: 24.00
+	Hs
		346438 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYC_HUMAN (36-135): 1.34e-30: 118: 24.00
+	Hs
		379230 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYCN_HUMAN (28-131): 6.54e-30: 116: 24.53
+	Hs
		607804 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF1_HUMAN (29-138): 5.1e-27: 106: 22.41
+	Hs
		917336 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		USF2_HUMAN (29-137): 3.89e-26: 104: 20.87
+	Hs
		379768 H4G_HUMAN (1-98): 1.04e-38: 126: 84.69		MYCN_HUMAN (28-131): 6.54e-30: 116: 24.53
+	Hs
		898095 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MAX_HUMAN (50-133): 3.97e-11: 61: 20.24
+	Hs
		917552 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MGAP_HUMAN (55-188): 7.05e-10: 59.8: 23.88
+	Hs
		585112 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TFEB_HUMAN (27-182): 7.79e-10: 59.4: 21.47
+	Hs
		252913 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MITF_HUMAN (40-138): 9.48e-09: 56.3: 23.30