HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: NUMA1 (Q14980)
Nuclear mitotic apparatus protein 1 (Nuclear matrix protein-22) (NMP-22) (Nuclear mitotic apparatus protein) (NuMA protein) (SP-H antigen)
Gene: NUMA1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	27248496, 30804502, 35271311
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex GO:0070062 - extracellular exosome
Homologous interactions	9

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 2115
+	Hs
		917856 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CP250_HUMAN (1-1659): 6.01e-59: 228: 13.08
+	Hs
		528404 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH8_HUMAN (1122-2115): 6.23e-35: 149: 10.31
+	Hs
		724750 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH9_HUMAN (1033-1891): 1.22e-33: 145: 10.62
+	Hs
		725132 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH10_HUMAN (1281-2075): 5.26e-33: 142: 12.34
+	Hs
		917302 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		EEA1_HUMAN (964-1838): 2.18e-28: 127: 12.15
+	Hs
		502906 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH3_HUMAN (930-1731): 1.32e-24: 115: 12.39
+	Hs
		728462 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		MYH11_HUMAN (1430-2076): 4.75e-22: 107: 8.41
+	Hs
		828572 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CENPF_HUMAN (1458-2037): 1.6e-10: 69.3: 9.97
+	Sc
		356275 H4_YEAST (18-103): 6.13e-41: 132: 90.70		USO1_YEAST (867-1693): 9.79e-11: 69.7: 18.63