HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: SRCAP (Q6ZRS2)
Helicase SRCAP (EC 3.6.4.-) (Domino homolog 2) (Snf2-related CBP activator)
Gene: SRCAP

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.56	1.00	0.754

Property	Details
Experiments	27248496, 30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Helicase_C, CENP-T_C~SNF2-rel_dom
Common GO terms	GO:0000786 - nucleosome GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0032991 - protein-containing complex
Homologous interactions	15

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 3230
+	Dm
		950383 H4_DROME (1-103): 4.51e-48: 150: 99.03		ISWI_DROME (2038-2356): 4.24e-100: 351: 34.57
+	Hs
		917277 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD4_HUMAN (1959-2633): 3.48e-89: 328: 19.60
+	Hs
		229352 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA5_HUMAN (2003-2357): 1.13e-90: 323: 28.77
+	Hs
		151483 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD2_HUMAN (2039-2386): 6.82e-78: 291: 27.90
+	Sc
		356774 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW2_YEAST (2003-2413): 3.62e-83: 301: 22.45
+	Hs
		918125 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		INO80_HUMAN (1894-2441): 1.39e-72: 272: 24.19
+	Sc
		356344 H4_YEAST (18-103): 6.13e-41: 132: 90.70		STH1_YEAST (2005-2548): 7.82e-78: 288: 21.35
+	Sc
		356248 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SNF2_YEAST (1969-2543): 2.4e-76: 285: 24.70
+	Hs
		917965 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD8_HUMAN (2021-2361): 3.76e-67: 256: 28.57
+	Hs
		917364 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CHD9_HUMAN (2026-2350): 4.5e-66: 253: 29.73
+	Sc
		356721 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SWR1_YEAST (1997-2303): 1.52e-70: 266: 50.81
+	Sc
		356424 H4_YEAST (18-103): 6.13e-41: 132: 90.70		ISW1_YEAST (2057-2345): 5.77e-70: 261: 30.77
+	Sc
		356605 H4_YEAST (18-103): 6.13e-41: 132: 90.70		INO80_YEAST (1949-2229): 2.19e-63: 242: 32.03
+	Hs
		846914 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA4_HUMAN (1505-1858): 9.38e-13: 76.9: 13.22
+	Hs
		917763 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		EP400_HUMAN (1085-1716): 1.74e-11: 73: 13.39