HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: PB1 (Q86U86)
Protein polybromo-1 (hPB1) (BRG1-associated factor 180) (BAF180) (Polybromo-1D)
Gene: PBRM1

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.66	1.00	0.814

Property	Details
Experiments	27248496, 30804502, 20368734
Identification Methods	affinity chromatography technology, unspecified method
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	BAH~CENP-T_C
Common GO terms	GO:0003677 - DNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Hs			1 1689
+	Hs
		641185 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		DNMT1_HUMAN (301-1361): 1.76e-75: 280: 12.20
+	Xl
		917053 H4_XENLA (1-103): 1.38e-48: 151: 100.00		P79922_XENLA (585-1361): 7.33e-72: 268: 13.31
+	Hs
		600119 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF1_HUMAN (457-963): 1.08e-57: 223: 16.79
+	Hs
		917576 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF1L_HUMAN (3-420): 2.75e-57: 221: 15.84
+	Hs
		917657 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PHIP_HUMAN (480-1024): 4.44e-53: 207: 13.50
+	Hs
		917299 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD3_HUMAN (358-959): 6.75e-48: 186: 12.76
+	Sc
		356667 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RSC4_YEAST (1-426): 1.18e-50: 192: 17.50
+	Sc
		356398 H4_YEAST (18-103): 6.13e-41: 132: 90.70		BDF1_YEAST (596-955): 2.06e-29: 128: 12.04
+	Hs
		917466 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRWD3_HUMAN (612-982): 1.38e-22: 108: 10.60
+	Mm
		918262 H4_MOUSE (1-103): 1.38e-48: 151: 100.00		BRDT_MOUSE (4-158): 1.5e-22: 107: 19.26
+	Hs
		631388 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD2_HUMAN (2-169): 7.14e-20: 98.6: 15.29
+	Sc
		356388 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SPT7_YEAST (8-587): 6.47e-25: 115: 12.13
+	Hs
		917895 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD8_HUMAN (301-506): 2.43e-17: 90.8: 14.55
+	Sp
		448927 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		YK82_SCHPO (2-153): 1.98e-21: 103: 16.88
+	Hs
		846914 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA4_HUMAN (764-881): 7.55e-11: 69.5: 23.58
+	Sc
		356614 H4_YEAST (18-103): 6.13e-41: 132: 90.70		RSC1_YEAST (389-658): 7.42e-11: 69.3: 13.57
+	Sc
		356344 H4_YEAST (18-103): 6.13e-41: 132: 90.70		STH1_YEAST (182-278): 9.89e-10: 65.9: 35.05
+	Sp
		448934 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		GCN5_SCHPO (208-293): 6.98e-09: 62.4: 32.56
+	Sc
		356248 H4_YEAST (18-103): 6.13e-41: 132: 90.70		SNF2_YEAST (389-487): 2.88e-09: 64.3: 34.34
+	Sc
		356682 H4_YEAST (18-103): 6.13e-41: 132: 90.70		GCN5_YEAST (546-625): 1.52e-09: 64.3: 41.25