Interactor 1: SLD3 (P53135)
DNA replication regulator SLD3
Gene: SLD3

Interactor 2: CDC45 (Q08032)
Cell division control protein 45
Gene: CDC45

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.96 0.90 0.932

The method score is based on:

Property Details
Experiments 25126958, 17167415, 20835227, 11296242, 26912723, 33683348, 21487389, 26305950, 29330352, 30595439, 21460226, 21362622
Identification Methods molecular sieving, two hybrid, pull down, affinity chromatography technology
Interaction Type direct interaction, physical association

The annotation score is based on:

Property Details
Interacting Pfam domains CDC45~Sld3_STD
Common GO terms GO:0000727 - double-strand break repair via break-induced replication
GO:0003682 - chromatin binding
GO:0005634 - nucleus
GO:0006270 - DNA replication initiation
GO:0031261 - DNA replication preinitiation complex
Homologous interactions 0

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Last updated: 11Aug2025