HitPredict

Interactor 1: KNL1 (P53148)
Outer kinetochore KNL1 complex subunit SPC105 (105 kDa spindle pole component protein) (Spindle pole body component SPC105)
Gene: SPC105

Interactor 2: ZWINT (Q04431)
Outer kinetochore KNL1 complex subunit KRE28 (Spindle pole body component KRE28)
Gene: KRE28

Species: Saccharomyces cerevisiae S288C

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.90 0.55 0.704

The method score is based on:

Property Details
Experiments 16554755, 19893618, 35042402, 37968396, 32997987, 14565975
Identification Methods affinity chromatography technology, two hybrid, biochemical, tandem affinity purification
Interaction Type physical association, direct interaction, association

The annotation score is based on:

Property Details
Interacting Pfam domains -
Common GO terms GO:0000776 - kinetochore
GO:0000940 - outer kinetochore
GO:0005634 - nucleus
GO:0031619 - homologous chromosome orientation in meiotic metaphase I
GO:0051382 - kinetochore assembly
and 1 others

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Homologous interactions 0

Service provided by Combinatics, Japan

Last updated: 11Aug2025