HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: H2A1J (Q99878)
Histone H2A type 1-J (Histone H2A/e)
Gene: H2AC14

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.60	1.00	0.776

Property	Details
Experiments	30021884, 37071682
Identification Methods	proximity labelling technology, cross-linking study
Interaction Type	physical association

Property	Details
Interacting Pfam domains	CENP-T_C~Histone, CENP-T_C~Histone_H2A_C
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0030527 - structural constituent of chromatin GO:0046982 - protein heterodimerization activity GO:0070062 - extracellular exosome
Homologous interactions	13

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 128
+	Hs
		917757 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1H_HUMAN (1-128): 2.98e-67: 200: 99.22
+	Hs
		391638 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1B_HUMAN (1-128): 1.31e-66: 199: 97.66
+	Hs
		470324 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1_HUMAN (1-128): 8.92e-67: 199: 99.22
+	Hs
		594838 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1D_HUMAN (1-128): 1.03e-66: 199: 98.44
+	Hs
		917438 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A2A_HUMAN (1-128): 6.49e-67: 199: 97.66
+	Hs
		917496 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A3_HUMAN (1-128): 9.73e-67: 199: 96.88
+	Hs
		917544 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A2B_HUMAN (1-128): 1.05e-66: 199: 95.31
+	Hs
		917699 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A1C_HUMAN (1-128): 8.17e-67: 199: 97.66
+	Hs
		917354 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2A2C_HUMAN (1-125): 3.22e-65: 195: 97.60
+	Hs
		555395 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		H2AX_HUMAN (1-124): 1.23e-63: 192: 94.36
+	Dm
		950379 H4_DROME (1-103): 4.51e-48: 150: 99.03		H2A_DROME (17-125): 5.28e-59: 179: 89.91
+	Sc
		356147 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H2A1_YEAST (16-126): 9.27e-53: 164: 81.08
+	Sc
		356148 H4_YEAST (18-103): 6.13e-41: 132: 90.70		H2A2_YEAST (16-126): 9.27e-53: 164: 81.08