HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: SLF1 (Q9BQI6)
SMC5-SMC6 complex localization factor protein 1 (Ankyrin repeat domain-containing protein 32) (BRCT domain-containing protein 1) (Smc5/6 localization factor 1)
Gene: SLF1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	1.00	0.618

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	Ank_2~CENP-T_C
Common GO terms	GO:0000781 - chromosome, telomeric region GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 103 Hs			1 1058
+	Hs
		917671 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TOPB1_HUMAN (2-240): 9.01e-85: 303: 24.13
+	Hs
		917128 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ANK2_HUMAN (691-1057): 5.67e-77: 280: 15.75
+	Hs
		917468 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		ANR11_HUMAN (750-927): 1.22e-41: 169: 39.11
+	Hs
		917809 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BARD1_HUMAN (790-935): 4.49e-42: 167: 41.22
+	Hs
		917742 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TONSL_HUMAN (796-943): 4.43e-36: 150: 38.00
+	Hs
		917472 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BCOR_HUMAN (712-931): 7.5e-34: 144: 27.48
+	Dm
		950404 H4_DROME (1-103): 4.51e-48: 150: 99.03		ANKHM_DROME (559-834): 1.61e-29: 130: 14.20
+	Hs
		917390 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BCORL_HUMAN (789-928): 9.22e-29: 127: 30.71