HitPredict

Interactor 1: H4 (P62805)
Histone H4
Gene: H4C1

Interactor 2: BRD8 (Q9H0E9)
Bromodomain-containing protein 8 (Skeletal muscle abundant protein) (Skeletal muscle abundant protein 2) (Thyroid hormone receptor coactivating protein of 120 kDa) (TrCP120) (p120)
Gene: BRD8

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30804502
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000786 - nucleosome GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006325 - chromatin organization
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 103 Hs			1 1235
+	Hs
		917179 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BPTF_HUMAN (130-1222): 5.45e-42: 171: 9.55
+	Hs
		917689 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT2B_HUMAN (1075-1209): 2.89e-37: 154: 23.70
+	Dm
		950422 H4_DROME (1-103): 4.51e-48: 150: 99.03		NU301_DROME (67-814): 1.41e-33: 143: 11.07
+	Hs
		170320 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TIF1A_HUMAN (845-1228): 4.33e-31: 134: 14.07
+	Hs
		918101 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BAZ2A_HUMAN (125-815): 2.72e-30: 132: 10.85
+	Sp
		448934 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		GCN5_SCHPO (603-815): 1.15e-35: 144: 17.84
+	Hs
		917979 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRD7_HUMAN (1005-1212): 3.07e-29: 127: 15.02
+	Hs
		917170 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		EP300_HUMAN (807-1211): 2.38e-27: 123: 13.66
+	Hs
		917517 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PB1_HUMAN (987-1226): 1.89e-22: 107: 15.45
+	Hs
		600119 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF1_HUMAN (1002-1220): 5.29e-22: 105: 15.32
+	Dm
		532730 H4_DROME (1-103): 4.51e-48: 150: 99.03		FSH_DROME (382-890): 3.91e-21: 102: 12.02
+	Sp
		448927 H4_SCHPO (18-103): 4.87e-42: 135: 89.54		YK82_SCHPO (843-1204): 8.83e-26: 116: 13.90
+	Hs
		917466 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		BRWD3_HUMAN (1048-1232): 1.82e-19: 97.4: 18.18
+	Hs
		917576 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		TAF1L_HUMAN (1101-1206): 4.22e-19: 96.3: 21.70
+	Hs
		846914 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		SMCA4_HUMAN (1057-1208): 7.26e-19: 95.5: 13.84
+	Zm
		19319 A0A1D6IAU4_MAIZE (1-103): 4.97e-53: 163: 98.06		A0A1D6HCG5_MAIZE (1084-1221): 7.63e-15: 81.5: 27.14
+	Dm
		950402 H4_DROME (1-103): 4.51e-48: 150: 99.03		Q9V9T4_DROME (715-809): 2.65e-16: 86.9: 30.53
+	Hs
		917657 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		PHIP_HUMAN (1059-1206): 1.19e-14: 81.5: 15.23
+	Hs
		917688 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		KAT2A_HUMAN (684-810): 1.1e-12: 74.9: 17.32
+	Hs
		917684 H4_HUMAN (1-103): 1.38e-48: 151: 100.00		CBP_HUMAN (125-595): 9.03e-09: 62.2: 12.22